Home > Products > BAFF & B7RP1 > Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Single-chain Diabody)

Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Single-chain Diabody)  (SCDB-018)

Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Single-chain Diabody) is designed to be expressed as one polypeptide chain with four variable domains from two parental antibodies. The middle linker is long enough to form scFv dimers between the two diabody chains. This BsAb can bind and inactivate two ligands simultaneously. It can inhibit B cell survival and T cell costimulation. It is designed for the research of Systemic lupus erythematosus (SLE) therapy.

Specifications
Targets
BAFF & B7RP1
Type
Single-chain Diabody
Species Reactivity
Human
Target 1
BAFF
Host Animal 1
Mouse
Target 2
B7RP1
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Systemic lupus erythematosus (SLE)
Targets
Target 1
BAFF
Gene ID
UniProt ID
Alternative Names
TNFSF13B; TNF superfamily member 13b; DTL; B cell activating factor; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNFSF20
Target 2
B7RP1
Gene ID
UniProt ID
Alternative Names
ICOSLG; inducible T cell costimulator ligand; B7H2; GL50; B7-H2; B7­related protein; B7RP1; CD275; ICOSL; LICOS; B7RP-1; ICOS-L

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