Name: Recombinant Human Anti-BCMA x Human Anti-CD3 Bispecific Antibody, IgG4 (BsIgG)
SKU: KN-0125-T2
Rating: 5 (1 reviews)

Recombinant Human Anti-BCMA x Human Anti-CD3 Bispecific Antibody (BsIgG) is designed to be expressed as four chains with Fc mutations to form heterodimers, the Fc backbone is human IgG4. It has the general size and structure of a conventional IgG. The Fc region also engineered to decrease Fc-mediated functions, but remains the half-life. This BsAb can retarget T cells to tumor cells. It is designed for the research of Multiple myeloma (MM) therapy.

Datasheet INQUIRY

Specifications

Targets

BCMA & CD3

Type

BsIgG

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Multiple myeloma (MM)

Host Animal 1

Human

Host Animal 2

Human

Targets

Target 1

BCMA

Gene ID

608

UniProt ID

Q02223

Alternative Names

TNFRSF17; tumor necrosis factor receptor superfamily, member 17; BCM; BCMA; CD269; TNFRSF13A; tumor necrosis factor receptor superfamily member 17; B-cell maturation factor; B cell maturation antigen; B-cell maturation protein

Target 2

CD3

Gene ID

916

UniProt ID

P07766

Alternative Names

CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-BCMA x Human Anti-CD3 Bispecific Antibody, IgG4 (BsIgG) (CAT#: KN-0125-T2)

Specifications

Targets

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