Name: Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (F(ab')2-scFv2)
SKU: BABFV-052
Rating: 5 (1 reviews)

Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-CD20 specificity is fused to the C terminus of the anti-CD47 Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can retarget macrophages to tumor cells. It is designed for the research of Lymphoma therapy.

Datasheet INQUIRY

Specifications

Targets

CD20 & CD47

Type

F(ab')2-scFv2

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Lymphoma

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

CD20

Gene ID

931

UniProt ID

A0A024R507

Alternative Names

MS4A1; membrane-spanning 4-domains, subfamily A, member 1; B1; S7; Bp35; CD20; CVID5; MS4A2; LEU-16; B-lymphocyte antigen CD20; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16; B-lymphocyte cell-surface antigen B1

Target 2

CD47

Gene ID

961

UniProt ID

Q08722

Alternative Names

CD47; CD47 molecule; IAP; OA3; MER6; leukocyte surface antigen CD47; CD47 glycoprotein; Rh-related antigen; integrin associated protein; integrin-associated protein; integrin-associated signal transducer; antigenic surface determinant protein OA3; antigen identified by monoclonal antibody 1D8; CD47 antigen (Rh-related antigen, integrin-associated signal transducer)

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (F(ab')2-scFv2) (CAT#: BABFV-052)

Specifications

Targets

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