Home > Products > CD28 & CSPG4 > Recombinant Human Anti-CD28 x Human Anti-CSPG4 Bispecific Antibody (scFv-Fc-scFv)

Recombinant Human Anti-CD28 x Human Anti-CSPG4 Bispecific Antibody (scFv-Fc-scFv)  (BSTF-H239)

Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-CD28 scFv is fused to the N-terminus of Fc via a hinge region while another anti-CSPG4 scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can retarget T cells to tumor cells. It is designed for the research of Melanoma therapy.

Specifications

Targets
CD28 & CSPG4
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
CD28
Host Animal 1
Mouse
Target 2
CSPG4
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Melanoma

Targets

Target 1
CD28
Gene ID
UniProt ID
Alternative Names
CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen
Target 2
CSPG4
Gene ID
UniProt ID
Alternative Names
NG2; Neuron-glial antigen 2; Melanoma-associated chondroitin sulfate proteoglycan; chondroitin sulfate proteoglycan 4; CSPG4; MCSP; MCSPG; MSK16; HMW-MAA; MEL-CSPG

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Human Anti-CD28 x Human Anti-CSPG4 Bispecific Antibody (scFv-Fc-scFv) (BSTF-H239). Click the button below to contact us or submit your feedback about this product.

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Welcome! For price inquiries, we will get back to you as soon as possible.

To order, please email

INQUIRY
Related products of "CD28 & CSPG4"
See other bsAb targets related to "CD28"

See other bsAb targets related to "CSPG4"

Online Inquiry

24x7 Service quality
USA

Tel:
Fax:
Email:

UK

Tel:
Email:

Germany

Tel:
Email: