Recombinant Anti-TG x Anti-TPO Bispecific Antibody (Diabody) is designed to be expressed as two polypeptide chains respectively. The two chains are cross-over pairing to form a dimer. It contains a His-tag for affinity purification. This BsAb can bind two antigens simultaneously and block the synthesis of thyroid hormones. It is designed for the research of Autoimmune thyroid disease therapy.