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IL4 Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
T-BSDB-H337 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (Tandem Diabody) Human Tandem Diabody IL13 Human IL4 Human Inquiry
T-BSDB-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Tandem Diabody) Human Tandem Diabody IL13 Mouse IL4 Mouse Inquiry
SCIGG-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (scIgG) Human Single chain IgGs IL13 Human IL4 Human Inquiry
SCIGG-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (scIgG) Human Single chain IgGs IL13 Mouse IL4 Mouse Inquiry
FVTIG-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (scFv4-Ig) Human scFv4-Ig IL13 Human IL4 Human Inquiry
FVTIG-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (scFv4-Ig) Human scFv4-Ig IL13 Mouse IL4 Mouse Inquiry
BSSG-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (scFv-IgG) Human scFv-IgG IL13 Human IL4 Human Inquiry
BSSG-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (scFv-IgG) Human scFv-IgG IL13 Mouse IL4 Mouse Inquiry
IGLFV-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv IL13 Human IL4 Human Inquiry
IGLFV-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv IL13 Mouse IL4 Mouse Inquiry
BSGV-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (IgG-Fv) Human IgG-Fv IL13 Mouse IL4 Mouse Inquiry
BSGV-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (IgG-Fv) Human IgG-Fv IL13 Mouse IL4 Mouse Inquiry
BSDG-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (Fv-IgG) Human Fv-IgG IL13 Human IL4 Human Inquiry
BSDG-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Fv-IgG) Human Fv-IgG IL13 Mouse IL4 Mouse Inquiry
BABFV-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 IL13 Human IL4 Human Inquiry
BABFV-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 IL13 Mouse IL4 Mouse Inquiry
FABVC-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc IL13 Human IL4 Human Inquiry
FABVC-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc IL13 Mouse IL4 Mouse Inquiry
SCDBC-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 IL13 Human IL4 Human Inquiry
SCDBC-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 IL13 Mouse IL4 Mouse Inquiry
BSDBC-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 IL13 Human IL4 Human Inquiry
BSDBC-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 IL13 Mouse IL4 Mouse Inquiry
SCDBF-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc IL13 Human IL4 Human Inquiry
SCDBF-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc IL13 Mouse IL4 Mouse Inquiry
BSFVF-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc IL13 Human IL4 Human Inquiry
BSFVF-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc IL13 Mouse IL4 Mouse Inquiry
BSDBF-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc IL13 Human IL4 Human Inquiry
BSDBF-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc IL13 Mouse IL4 Mouse Inquiry
BSTF-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv IL13 Mouse IL4 Mouse Inquiry
BSTF-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv IL13 Mouse IL4 Mouse Inquiry
BSCFV-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (scFv-Fc) Human scFv-Fc IL13 Mouse IL4 Mouse Inquiry
BSCFV-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (scFv-Fc) Human scFv-Fc IL13 Mouse IL4 Mouse Inquiry
MNAB-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (Miniantibody) Human Miniantibody IL13 Mouse IL4 Mouse Inquiry
MNAB-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Miniantibody) Human Miniantibody IL13 Mouse IL4 Mouse Inquiry
BSFC-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (scFv-CH3) Human scFv-CH3 IL13 Mouse IL4 Mouse Inquiry
BSFC-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (scFv-CH3) Human scFv-CH3 IL13 Mouse IL4 Mouse Inquiry
BSCC-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL IL13 Mouse IL4 Mouse Inquiry
BSCC-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL IL13 Mouse IL4 Mouse Inquiry
BIBD-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (Bibody) Human Bibody IL13 Mouse IL4 Mouse Inquiry
BIBD-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Bibody) Human Bibody IL13 Mouse IL4 Mouse Inquiry
FABFV-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (Fab-Fv) Human Fab-Fv IL13 Human IL4 Human Inquiry
FABFV-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Fab-Fv) Human Fab-Fv IL13 Mouse IL4 Mouse Inquiry
MiniB-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (Minibody) Human Minibody IL13 Human IL4 Human Inquiry
MiniB-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Minibody) Human Minibody IL13 Mouse IL4 Mouse Inquiry
SCDB-H337 Recombinant Human Anti-IL13 x Anti-IL4 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody IL13 Human IL4 Human Inquiry
FABIG-H337 Recombinant Human Anti-IL13 x Anti-IL4 Bispecific Antibody (Fab-IgG) Human Fab-IgG IL13 Human IL4 Human Inquiry
TRIB-H339 Recombinant Human Anti-IL13 x Anti-IL4 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv IL13 Human IL4 Human Inquiry
BSIG-H337 Human Anti-IL13 x Anti-IL4 Bispecific Antibody (IgG-IgG) Human IgG-IgG IL13 Human IL4 Human Inquiry
CROSSAB-H337 Recombinant Human Anti-IL13 x Anti-IL4 Bispecific Antibody (CrossMab) Human CrossMab IL13 Human IL4 Human Inquiry
IGFV-H337 Recombinant Human Anti-IL13 x Anti-IL4 Bispecific Antibody (IgG-scFv) Human IgG-scFv IL13 Human IL4 Human Inquiry
BSDB-H337 Recombinant Human Anti-IL13 x Anti-IL4 Bispecific Antibody (Diabody) Human Diabody IL13 Human IL4 Human Inquiry
BSFAB-H337 Recombinant Human Anti-IL13 x Anti-IL4 Bispecific Antibody (Tandem Fab) Human Tandem Fab IL13 Human IL4 Human Inquiry
BSFV-H335 Recombinant Human Anti-IL13 x Anti-IL4 Bispecific Antibody (Tandem scFv) Human Tandem scFv IL13 Human IL4 Human Inquiry
SCDB-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody IL13 Mouse IL4 Mouse Inquiry
FABIG-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Fab-IgG) Human Fab-IgG IL13 Mouse IL4 Mouse Inquiry
TRIB-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv IL13 Mouse IL4 Mouse Inquiry
BSIG-173 Anti-IL13 x Anti-IL4 Bispecific Antibody (IgG-IgG) Human IgG-IgG IL13 Mouse IL4 Mouse Inquiry
CROSSAB-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (CrossMab) Human CrossMab IL13 Mouse IL4 Mouse Inquiry
IGFV-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (IgG-scFv) Human IgG-scFv IL13 Mouse IL4 Mouse Inquiry
BSDB-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Diabody) Human Diabody IL13 Mouse IL4 Mouse Inquiry
BSFAB-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Tandem Fab) Human Tandem Fab IL13 Mouse IL4 Mouse Inquiry
BSFV-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Tandem scFv) Human Tandem scFv IL13 Mouse IL4 Mouse Inquiry

Background

Fig. 1 IL4 receptor-mediated signaling. (McCormick, et al., 2015)Fig. 1 IL4 receptor-mediated signaling.1

Interleukin 4 (IL4) also known as B-cell stimulatory factor 1 or T-cell growth factor 2, is a pleiotropic cytokine with immunomodulatory effects on B cells, T cells, mast cells, macrophages, and hematopoietic cells. There are two types of receptors for IL4. Type I receptor is specific for IL4. Type II receptor is a receptor complex consisting of IL4Rα and IL13Rα1 and therefore are also responsive to IL13. IL4 and IL13 are structurally and functionally related cytokines. They are key cytokines in the induction and maintenance of type II inflammatory responses, which have been implicated in a variety of atopic diseases such as atopic dermatitis, asthma, and chronic sinusitis with nasal polyposis. In addition, the upregulation of IL4 and IL13 receptors on the surface of tumor cells has been found in cancer studies, including breast cancer and lymphoma.

Reference

  1. McCormick, S.M.; Heller, N.M. Commentary: IL-4 and IL-13 receptors and signaling. Cytokine. 2015, 75(1): 38-50.
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