Anti-AANAT Aptamer SELEX Service(Cat#: CTApt-2501)
This is an aptamer development services to screening aptamers binds to the AANAT with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
AANAT |
| Alternative Names |
Aralkylamine N-Acetyltransferase; Serotonin N-Acetyltransferase; SNAT; Arylalkylamine N-Acetyltransferase; Serotonin Acetylase; EC 2.3.1.87; AA-NAT; AANAT; DSPS |
| Gene ID |
15 |
| UniProt ID |
Q16613 |
| Target Overview |
The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
