This is an aptamer development services to screening aptamers binds to the AASS with an affinity of 1nM~1μM.
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
| Target Category | Protein |
| Target | AASS |
| Alternative Names | Aminoadipate-Semialdehyde Synthase; Alpha-Aminoadipic Semialdehyde Synthase, Mitochondrial; LKR/SDH; LKRSDH; LORSDH; Lysine-Ketoglutarate Reductase /Saccharopine Dehydrogenase; Lysine Ketoglutarate Reductase/Saccharopine Dehydrogenase; Alpha-Aminoadipate Semialdehyde Synthase; Alpha-Aminoadipic Semialdehyde Synthase; Aminoadipic Semialdehyde Synthase; Lysine-2-Oxoglutarate Reductase; AASS |
| Gene ID | 10157 |
| UniProt ID | Q9UDR5 |
| Target Overview | This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |