This is an aptamer development services to screening aptamers binds to the AATK with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | AATK |
| Alternative Names | Apoptosis Associated Tyrosine Kinase; Lemur Tyrosine Kinase 1; AATYK; LMTK1; LMR1; Protein Phosphatase 1, Regulatory Subunit 77; Brain Apoptosis-Associated Tyrosine Kinase; Serine/Threonine-Protein Kinase LMTK1; CDK5-Binding Protein; P35-Binding Protein; EC 2.7.11.1; KIAA0641; PPP1R77; AATYK1; P35BP; Apoptosis-Associated Tyrosine Kinase; EC 2.7.11; AATK |
| Gene ID | 9625 |
| UniProt ID | Q6ZMQ8 |
| Target Overview | The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |