Anti-ABCB11 Aptamer SELEX Service(Cat#: CTApt-2425)
This is an aptamer development services to screening aptamers binds to the ABCB11 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ABCB11 |
| Alternative Names |
ATP Binding Cassette Subfamily B Member 11; Bile Salt Export Pump; ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11; Progressive Familial Intrahepatic Cholestasis 2; ATP-Binding Cassette Sub-Family B Member 11; ABC Member 16, MDR/TAP Subfamily; PFIC-2; ABC16; BSEP; PGY4; SPGP; Sister P-Glycoprotein; EC 3.6.3.44; EC 7.6.2.- ; EC 3.6.3; ABCB11; BRIC2; PFIC2 |
| Gene ID |
8647 |
| UniProt ID |
O95342 |
| Target Overview |
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
