Anti-ABCB7 Aptamer SELEX Service(Cat#: CTApt-897)
This is an aptamer development services to screening aptamers binds to the ABCB7 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ABCB7 |
| Alternative Names |
ATP Binding Cassette Subfamily B Member 7; ATP-Binding Cassette Sub-Family B Member 7, Mitochondrial; ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7; ATP-Binding Cassette Transporter 7; ABC Transporter 7 Protein; EST140535; Atm1p; ABC7; ASAT; EC 3.6.3.42; EC 3.6.3; ABCB7 |
| Gene ID |
22 |
| UniProt ID |
O75027 |
| Target Overview |
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
