Anti-ABCC12 Aptamer SELEX Service(Cat#: CTApt-1248)

This is an aptamer development services to screening aptamers binds to the ABCC12 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ABCC12
Alternative Names ATP Binding Cassette Subfamily C Member 12; MRP9; ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 12; ATP-Binding Cassette Sub-Family C Member 12; Multidrug Resistance-Associated Protein 9; ATP-Binding Cassette Transporter Sub-Family C Member 12; ABCC12
Gene ID 94160
UniProt ID Q96J65
Target Overview This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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