This is an aptamer development services to screening aptamers binds to the ABCC4 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ABCC4 |
| Alternative Names | ATP Binding Cassette Subfamily C Member 4; Multidrug Resistance-Associated Protein 4; MOAT-B; MRP4; Canalicular Multispecific Organic Anion Transporter (ABC Superfamily) ; BA464I2.1 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4) ; Multi-Specific Organic Anion Transporter B; MRP/CMOAT-Related ABC Transporter; MOATB; ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4; ATP-Binding Cassette Sub-Family C Member 4; Multispecific Organic Anion Transporter B; EST170205; ABCC4 |
| Gene ID | 10257 |
| UniProt ID | O15439 |
| Target Overview | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |