Anti-ABCC4 Aptamer SELEX Service(Cat#: CTApt-900)

This is an aptamer development services to screening aptamers binds to the ABCC4 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ABCC4
Alternative Names ATP Binding Cassette Subfamily C Member 4; Multidrug Resistance-Associated Protein 4; MOAT-B; MRP4; Canalicular Multispecific Organic Anion Transporter (ABC Superfamily) ; BA464I2.1 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4) ; Multi-Specific Organic Anion Transporter B; MRP/CMOAT-Related ABC Transporter; MOATB; ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4; ATP-Binding Cassette Sub-Family C Member 4; Multispecific Organic Anion Transporter B; EST170205; ABCC4
Gene ID 10257
UniProt ID O15439
Target Overview The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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