Anti-ABCD4 Aptamer SELEX Service(Cat#: CTApt-902)
This is an aptamer development services to screening aptamers binds to the ABCD4 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ABCD4 |
| Alternative Names |
ATP Binding Cassette Subfamily D Member 4; PMP69; P70R; ATP-Binding Cassette, Sub-Family D (ALD), Member 4; ATP-Binding Cassette Sub-Family D Member 4; Lysosomal Cobalamin Transporter ABCD4; Peroxisomal Membrane Protein 69; PMP70-Related Protein; EST352188; PXMP1-L; PXMP1L; Peroxisomal Membrane Protein 1-Like; 69 KDa Peroxisomal ABC-Transporter; ABC41; MAHCJ; ABCD4; P79R |
| Gene ID |
5826 |
| UniProt ID |
O14678 |
| Target Overview |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in several protein-coding and non-protein-coding variants. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
