Anti-ABHD12 Aptamer SELEX Service(Cat#: CTApt-1320)
This is an aptamer development services to screening aptamers binds to the ABHD12 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ABHD12 |
| Alternative Names |
Abhydrolase Domain Containing 12, Lysophospholipase; Abhydrolase Domain Containing 12; Oxidized Phosphatidylserine Lipase ABHD12; Abhydrolase Domain-Containing Protein 12; 2-Arachidonoylglycerol Hydrolase ABHD12; Lysophosphatidylserine Lipase ABHD12; Monoacylglycerol Lipase ABHD12; EC 3.1.1.23; DJ965G21.2; C20orf22; ABHD12A; BEM46L2; HABHD12; Chromosome 20 Open Reading Frame 22; 2-Arachidonoylglycerol Hydrolase; DKFZP434P106; ABHD12; PHARC |
| Gene ID |
26090 |
| UniProt ID |
Q8N2K0 |
| Target Overview |
This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
