Anti-ABI3 Aptamer SELEX Service(Cat#: CTApt-921)

This is an aptamer development services to screening aptamers binds to the ABI3 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ABI3
Alternative Names ABI Family Member 3; NESH; New Molecule Including SH3; ABI Gene Family Member 3; SSH3BP3; ABI Family, Member 3; ABI3; Nesh
Gene ID 51225
UniProt ID Q9P2A4
Target Overview This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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