This is an aptamer development services to screening aptamers binds to the ACADVL with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ACADVL |
| Alternative Names | Acyl-CoA Dehydrogenase Very Long Chain; VLCAD; Very Long-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial; Acyl-Coenzyme A Dehydrogenase, Very Long Chain; ACAD6; LCACD; EC 1.3.8.9; EC 1.3.99; ACADVL |
| Gene ID | 37 |
| UniProt ID | P49748 |
| Target Overview | The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |