Anti-ACIN1 Aptamer SELEX Service(Cat#: CTApt-2539)

This is an aptamer development services to screening aptamers binds to the ACIN1 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ACIN1
Alternative Names Apoptotic Chromatin Condensation Inducer 1; Apoptotic Chromatin Condensation Inducer In The Nucleus; Functional Spliceosome-Associated Protein 152; KIAA0670; FSAP152; ACINUS; Acinus; ACIN1; ACN
Gene ID 22985
UniProt ID Q9UKV3
Target Overview Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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