Anti-ACLY Aptamer SELEX Service(Cat#: CTApt-950)

This is an aptamer development services to screening aptamers binds to the ACLY with an affinity of 1nM~1μM.

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Lot Number

TOP
Summary

Specifications
Target Category Protein
Target ACLY
Alternative Names ATP Citrate Lyase; ACL; ATP-Citrate (Pro-S-)-Lyase; Citrate Cleavage Enzyme; ATP-Citrate Synthase; EC 2.3.3.8; ATPCL; CLATP; ATP Citrate Synthase; ACLY
Gene ID 47
UniProt ID P53396
Target Overview ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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