Anti-ACMSD Aptamer SELEX Service(Cat#: CTApt-1376)

This is an aptamer development services to screening aptamers binds to the ACMSD with an affinity of 1nM~1μM.

Datasheet MSDS COA
Specific Inquiry 
Size
5’ Modification
 
3’ Modification
 
Add To
Online Inquiry

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number

TOP
Summary

Specifications
Target Category Protein
Target ACMSD
Alternative Names Aminocarboxymuconate Semialdehyde Decarboxylase; 2-Amino-3-Carboxymuconate-6-Semialdehyde Decarboxylase; Picolinate Carboxylase; EC 4.1.1.45; ACMSD
Gene ID 130013
UniProt ID Q8TDX5
Target Overview The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
Online Inquiry
×