This is an aptamer development services to screening aptamers binds to the ACOX2 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ACOX2 |
| Alternative Names | Acyl-CoA Oxidase 2; 3-Alpha,7-Alpha,12-Alpha-Trihydroxy-5-Beta-Cholestanoyl-CoA 24-Hydroxylase; Trihydroxycoprostanoyl-CoA Oxidase; THCCox; 3-Alpha,7-Alpha,12-Alpha-Trihydroxy-5-Beta-Cholestanoyl-CoA Oxidase; Acyl-Coenzyme A Oxidase 2, Branched Chain; Peroxisomal Acyl-Coenzyme A Oxidase 2; Acyl-CoA Oxidase 2, Branched Chain; Branched Chain Acyl-CoA Oxidase; THCA-CoA Oxidase; BRCACOX; BRCOX; Peroxisomal Branched Chain Acyl-CoA Oxidase; EC 1.17.99.3; CBAS6; ACOX2; BCOX |
| Gene ID | 8309 |
| UniProt ID | Q99424 |
| Target Overview | The product of this gene belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe cognitive disability, and death in children. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |