This is an aptamer development services to screening aptamers binds to the ACSL6 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ACSL6 |
| Alternative Names | Acyl-CoA Synthetase Long Chain Family Member 6; LACS5; ACS2; Fatty-Acid-Coenzyme A Ligase, Long-Chain 6; Long-Chain-Fatty-Acid--CoA Ligase 6; Arachidonate--CoA Ligase; EC 6.2.1.3; KIAA0837; LACS 6; FACL6; LACS2; Long Fatty Acyl-CoA Synthetase 2; Long-Chain Acyl-CoA Synthetase 6; EC 6.2.1.15; EC 6.2.1; ACSL6 |
| Gene ID | 23305 |
| UniProt ID | Q9UKU0 |
| Target Overview | The protein encoded by this gene catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |