Anti-ACTA1 Aptamer SELEX Service(Cat#: CTApt-976)
This is an aptamer development services to screening aptamers binds to the ACTA1 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ACTA1 |
| Alternative Names |
Actin Alpha 1, Skeletal Muscle; Actin, Alpha Skeletal Muscle; Nemaline Myopathy Type 3; ACTA; NEM3; Alpha-Actin-1; CFTD1; CFTDM; ACTA1; ASMA; CFTD; MPFD; NEM1; NEM2; SHPM |
| Gene ID |
58 |
| UniProt ID |
P68133 |
| Target Overview |
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause a variety of myopathies, including nemaline myopathy, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects with manifestations such as hypotonia. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
