Anti-ACVR1B Aptamer SELEX Service(Cat#: CTApt-993)

This is an aptamer development services to screening aptamers binds to the ACVR1B with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ACVR1B
Alternative Names Activin A Receptor Type 1B; ALK4; SKR2; Serine/Threonine-Protein Kinase Receptor R2; Activin Receptor-Like Kinase 4; Activin A Receptor, Type IB; Activin Receptor Type-1B; EC 2.7.11.30; ACVRLK4; Activin A Receptor, Type II-Like Kinase 4; Activin Receptor Type IB; EC 2.7.11; ACTR-IB; ACTRIB; ACVR1B; ActRIB; ALK-4
Gene ID 91
UniProt ID P36896
Target Overview This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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