Anti-ACVR2A Aptamer SELEX Service(Cat#: CTApt-995)
This is an aptamer development services to screening aptamers binds to the ACVR2A with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ACVR2A |
| Alternative Names |
Activin A Receptor Type 2A; Activin A Receptor, Type IIA; Activin Receptor Type-2A; EC 2.7.11.30; ACTRII; ACVR2; Activin A Receptor, Type II; Activin Receptor Type IIA; EC 2.7.11; ACTR-IIA; ACTRIIA; ACVR2A |
| Gene ID |
92 |
| UniProt ID |
P27037 |
| Target Overview |
This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
