Anti-ACVRL1 Aptamer SELEX Service(Cat#: CTApt-997)
This is an aptamer development services to screening aptamers binds to the ACVRL1 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ACVRL1 |
| Alternative Names |
Activin A Receptor Like Type 1; ALK1; Serine/Threonine-Protein Kinase Receptor R3; Activin A Receptor Type II-Like 1; TGF-B Superfamily Receptor Type I; Activin Receptor-Like Kinase 1; Activin A Receptor Type IL; EC 2.7.11.30; ACVRLK1; ALK-1; TSR-I; HHT2; SKR3; HHT; Activin A Receptor, Type II-Like Kinase 1; EC 2.7.11; ACVRL1; ORW2 |
| Gene ID |
94 |
| UniProt ID |
P37023 |
| Target Overview |
This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
