Anti-ADAM11 Aptamer SELEX Service(Cat#: CTApt-1277)
This is an aptamer development services to screening aptamers binds to the ADAM11 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ADAM11 |
| Alternative Names |
ADAM Metallopeptidase Domain 11; Metalloproteinase-Like, Disintegrin-Like, And Cysteine-Rich Protein; Disintegrin And Metalloproteinase Domain-Containing Protein 11; ADAM 11; MDC; Metalloproteinase-Like, Disintegrin-Like, Cysteine-Rich Protein; A Disintegrin And Metalloproteinase Domain 11; ADAM11 |
| Gene ID |
4185 |
| UniProt ID |
O75078 |
| Target Overview |
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. This gene represents a candidate tumor suppressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
