This is an aptamer development services to screening aptamers binds to the ADAMTS15 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ADAMTS15 |
| Alternative Names | ADAM Metallopeptidase With Thrombospondin Type 1 Motif 15; A Disintegrin And Metalloproteinase With Thrombospondin Motifs 15; ADAM-TS 15; ADAM-TS15; ADAMTS-15; A Disintegrin-Like And Metalloprotease (Reprolysin Type) With Thrombospondin Type 1 Motif, 15, Preproprotein; A Disintegrin-Like And Metalloprotease (Reprolysin Type) With Thrombospondin Type 1 Motif, 15; Metalloprotease Disintegrin 15 With Thrombospondin Domains; EC 3.4.24.82; EC 3.4.24.14; EC 3.4.24.- ; EC 3.4.24; ADAMTS15 |
| Gene ID | 170689 |
| UniProt ID | Q8TE58 |
| Target Overview | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme, which may play a role in versican processing during skeletal muscle development. This gene may function as a tumor suppressor in colorectal and breast cancers. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |