This is an aptamer development services to screening aptamers binds to the ADAMTS17 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ADAMTS17 |
| Alternative Names | ADAM Metallopeptidase With Thrombospondin Type 1 Motif 17; A Disintegrin-Like And Metalloprotease (Reprolysin Type) With Thrombospondin Type 1 Motif, 17; A Disintegrin And Metalloproteinase With Thrombospondin Motifs 17; EC 3.4.24.82; EC 3.4.24.80; EC 3.4.24.- ; ADAM-TS 17; ADAM-TS17; ADAMTS-17; EC 3.4.24; ADAMTS17; FLJ32769; FLJ16363; WMS4 |
| Gene ID | 170691 |
| UniProt ID | Q8TE56 |
| Target Overview | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may promote breast cancer cell growth and survival. Mutations in this gene are associated with a Weill-Marchesani-like syndrome, which is characterized by lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |