Anti-ADAMTS2 Aptamer SELEX Service(Cat#: CTApt-1207)

This is an aptamer development services to screening aptamers binds to the ADAMTS2 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ADAMTS2
Alternative Names ADAM Metallopeptidase With Thrombospondin Type 1 Motif 2; Procollagen N-Endopeptidase; Procollagen I N-Proteinase; ADAM-TS2; PCINP; A Disintegrin-Like And Metalloprotease (Reprolysin Type) With Thrombospondin Type 1 Motif, 2; A Disintegrin And Metalloproteinase With Thrombospondin Motifs 2; Procollagen I/II Amino Propeptide-Processing Enzyme; EC 3.4.24.14; ADAMTS-2; ADAMTS-3; PC I-NP; PCPNI; PNPI; NPI; ADAM-TS 2; EC 3.4.24; EDSDERMS; ADAMTS2; PCI-NP; HPCPNI
Gene ID 9509
UniProt ID O95450
Target Overview This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature procollagen N-proteinase. This proteinase excises the N-propeptide of the fibrillar procollagens types I-III and type V. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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