This is an aptamer development services to screening aptamers binds to the ADCY5 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ADCY5 |
| Alternative Names | Adenylate Cyclase 5; AC5; ATP Pyrophosphate-Lyase 5; Adenylate Cyclase Type 5; Adenylate Cyclase Type V; Adenylyl Cyclase 5; EC 4.6.1.1; Epididymis Secretory Sperm Binding Protein; ADCY5; FDFM |
| Gene ID | 111 |
| UniProt ID | O95622 |
| Target Overview | This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |