This is an aptamer development services to screening aptamers binds to the ADCY8 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ADCY8 |
| Alternative Names | Adenylate Cyclase 8; AC8; Ca(2+)/Calmodulin-Activated Adenylyl Cyclase; Adenylate Cyclase 8 (Brain) ; Adenylate Cyclase Type VIII; ATP Pyrophosphate-Lyase 8; Adenylate Cyclase Type 8; Adenylyl Cyclase 8; EC 4.6.1.1; HBAC1; Epididymis Secretory Sperm Binding Protein Li 172mP; Adenylyl Cyclase-8, Brain; HEL-S-172m; ADCY3; ADCY8 |
| Gene ID | 114 |
| UniProt ID | P40145 |
| Target Overview | Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |