Anti-AFF2 Aptamer SELEX Service(Cat#: CTApt-2475)

This is an aptamer development services to screening aptamers binds to the AFF2 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target AFF2
Alternative Names AF4/FMR2 Family Member 2; Fragile X E Mental Retardation Syndrome Protein; Fragile X Mental Retardation 2 Protein; Protein FMR-2; FMR2P; FRAXE; FMR2; OX19; Fragile X Mental Retardation 2; AF4/FMR2 Family, Member 2; Protein Ox19; MRX2; AFF2
Gene ID 2334
UniProt ID P51816
Target Overview This gene encodes a putative transcriptional activator that is a member of the AF4\FMR2 gene family. This gene is associated with the folate-sensitive fragile X E locus on chromosome X. A repeat polymorphism in the fragile X E locus results in silencing of this gene causing Fragile X E syndrome. Fragile X E syndrome is a form of nonsyndromic X-linked cognitive disability. In addition, this gene contains 6-25 GCC repeats that are expanded to>200 repeats in the disease state. Alternate splicing results in multiple transcript variants.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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