This is an aptamer development services to screening aptamers binds to the AGO3 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | AGO3 |
| Alternative Names | Argonaute RISC Catalytic Component 3; Eukaryotic Translation Initiation Factor 2C, 3; Protein Argonaute-3; EIF2C3; HAgo3; Eukaryotic Translation Initiation Factor 2C 3; Argonaute 3, RISC Catalytic Component; EC 3.1.26.n2; Argonaute 3; Argonaute3; FLJ12765; EIF-2C 3; EIF2C 3; HAGO3; AGO3 |
| Gene ID | 192669 |
| UniProt ID | Q9H9G7 |
| Target Overview | This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a tandem cluster of closely related family members including argonaute 4 and eukaryotic translation initiation factor 2C, 1. Two transcript variants encoding distinct isoforms have been identified for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |