Anti-AKR7L Aptamer SELEX Service(Cat#: CTApt-1482)

This is an aptamer development services to screening aptamers binds to the AKR7L with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target AKR7L
Alternative Names Aldo-Keto Reductase Family 7 Like (Gene/Pseudogene) ; AFAR3; Aflatoxin B1 Aldehyde Reductase Member 4; Aldo-Keto Reductase Family 7-Like; AFB1 Aldehyde Reductase 3; Aldoketoreductase 7-Like; AFB1-AR 3; AKR7A4; Aldo-Keto Reductase Family 7 Pseudogene; AFB1-AR3; AKR7L
Gene ID 246181
UniProt ID Q8NHP1
Target Overview This gene is one of three aldo-keto reductase genes that are present in a cluster on the p arm of chromosome 1. The encoded proteins are involved in the reduction of the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. It has been speculated that this family member encodes a selenoprotein, which includes a selenocysteine (Sec) residue in lieu of a UGA translational termination codon. However, there is no evidence that such a protein is produced in vivo. The alternative interpretation is that this family member is a segregating pseudogene, where some individuals have an allele that encodes a functional enzyme, while other individuals have an allele encoding a protein that is predicted to be non-functional.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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