This is an aptamer development services to screening aptamers binds to the AKT1S1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | AKT1S1 |
| Alternative Names | AKT1 Substrate 1; PRAS40; 40 KDa Proline-Rich AKT Substrate; Proline-Rich AKT1 Substrate 1; Lobe; Proline-Rich Akt Substrate, 40 KDa; AKT1 Substrate 1 (Proline-Rich) ; AKT1 Substrate 1 (Proline Rich) ; MGC2865; AKT1S1; |
| Gene ID | 84335 |
| UniProt ID | Q96B36 |
| Target Overview | AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]). |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |