This is an aptamer development services to screening aptamers binds to the ALDH4A1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ALDH4A1 |
| Alternative Names | Aldehyde Dehydrogenase 4 Family Member A1; L-Glutamate Gamma-Semialdehyde Dehydrogenase; Delta-1-Pyrroline-5-Carboxylate Dehydrogenase, Mitochondrial; Aldehyde Dehydrogenase Family 4 Member A1; P5C Dehydrogenase; ALDH4; P5CDh; Mitochondrial Delta-1-Pyrroline 5-Carboxylate Dehydrogenase; Delta-1-Pyrroline-5-Carboxylate Dehydrogenase; Aldehyde Dehydrogenase 4 Family, Member A1; Epididymis Secretory Sperm Binding Protein; EC 1.5.1.12; EC 1.2.1.88; ALDH4A1; P5CDH; P5CD |
| Gene ID | 8659 |
| UniProt ID | P30038 |
| Target Overview | This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |