Anti-Aldosterone Aptamer(Cat#: CTApt-2563)
This product is an aptamer which binds to the Aldosterone with an affinity of <10 µM.
Specific Inquiry 
Specifications
| Target Category |
Small Organic |
| Target |
Aldosterone |
| Alternative Names |
ALDOSTERONE; 52-39-1; Electrocortin; Aldocortin; Aldocorten |
| Target Overview |
Aldosterone is a mineralocorticoid hormone produced by aldosterone synthase (CYP11B2) in the zona glomerulosa of the adrenal cortex. Aldosterone binds to mineralocorticoid receptors (MR; NR3C2) and MR-aldosterone complexes regulate the expression of genes involved in the retention of sodium, the secretion of potassium, and water reabsorption, all of which may result increased blood pressure. |
| Chemical Modification |
DNA |
| Length |
20-40 nt |
| Affinity (Kd) |
<10 µM |
| Binding Conditions/Buffer |
20 mM HEPES, 1 M NaCl, 10 mM MgCl2, 5 mM KCl, pH 7.5 |
| GC Content |
44% |
| Molecular Weight |
11112.3 |
| nmoles/OD260 |
2.646 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
