This is an aptamer development services to screening aptamers binds to the ALOX12 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ALOX12 |
| Alternative Names | Arachidonate 12-Lipoxygenase, 12S Type; 12S-LOX; Polyunsaturated Fatty Acid Lipoxygenase ALOX12; Arachidonate 12-Lipoxygenase, 12S-Type; Arachidonate (12S)-Lipoxygenase; Arachidonate (15S)-Lipoxygenase; Platelet-Type Lipoxygenase 12; Lipoxin Synthase 12-LO; 12S-Lipoxygenase; Platelet 12-LOX; LOG12; Arachidonate 15-Lipoxygenase,15S-Type; Platelet-Type 12-Lipoxygenase; Arachidonate 12-Lipoxygenase; Linoleate (13S)-Lipoxygenase; Linoleate 13S-Lipoxygenase; 12-LOX; ALOX12; 12LO |
| Gene ID | 239 |
| UniProt ID | P18054 |
| Target Overview | This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on different polyunsaturated fatty acid substrates to generate bioactive lipid mediators including eicosanoids and lipoxins. The encoded enzyme and its reaction products have been shown to regulate platelet function. Elevated expression of this gene has been observed in pancreatic islets derived from human diabetes patients. Allelic variants in this gene may be associated with susceptibility to toxoplasmosis. Multiple pseudogenes of this gene have been identified in the human genome. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |