This is an aptamer development services to screening aptamers binds to the AMFR with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | AMFR |
| Alternative Names | Autocrine Motility Factor Receptor; RNF45; RING-Type E3 Ubiquitin Transferase AMFR; E3 Ubiquitin-Protein Ligase AMFR; RING Finger Protein 45; Gp78; AMF Receptor; EC 2.3.2.27; GP78; AMFR |
| Gene ID | 267 |
| UniProt ID | Q9UKV5 |
| Target Overview | This locus encodes a glycosylated transmembrane receptor. Its ligand, autocrine motility factor, is a tumor motility-stimulating protein secreted by tumor cells. The encoded receptor is also a member of the E3 ubiquitin ligase family of proteins. It catalyzes ubiquitination and endoplasmic reticulum-associated degradation of specific proteins. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |