Anti-AMPD1 Aptamer SELEX Service(Cat#: CTApt-2429)

This is an aptamer development services to screening aptamers binds to the AMPD1 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target AMPD1
Alternative Names Adenosine Monophosphate Deaminase 1; Adenosine Monophosphate Deaminase 1 (Isoform M) ; Myoadenylate Deaminase; Skeletal Muscle AMPD; AMP Deaminase 1; EC 3.5.4.6; MADA; MAD; Adenosine Monophosphate Deaminase-1 (Muscle) ; AMP Deaminase Isoform M; AMPD Isoform M; AMPD1; MMDD; AMPD
Gene ID 270
UniProt ID P23109
Target Overview Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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