This is an aptamer development services to screening aptamers binds to the AMPH with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | AMPH |
| Alternative Names | Amphiphysin; Amphiphysin (Stiff-Mann Syndrome With Breast Cancer 128kD Autoantigen) ; AMPH1; Amphiphysin (Stiff-Man Syndrome With Breast Cancer 128kDa Autoantigen) ; Amphiphysin I; AMPH |
| Gene ID | 273 |
| UniProt ID | P49418 |
| Target Overview | This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |