Anti-ANO3 Aptamer SELEX Service(Cat#: CTApt-1348)

This is an aptamer development services to screening aptamers binds to the ANO3 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ANO3
Alternative Names Anoctamin 3; Transmembrane Protein 16C (Eight Membrane-Spanning Domains) ; Transmembrane Protein 16C; Dystonia 23; Anoctamin-3; GENX-3947; C11orf25; TMEM16C; DYT23; Chromosome 11 Open Reading Frame 25; DYT24; ANO3
Gene ID 63982
UniProt ID Q9BYT9
Target Overview The protein encoded by this gene belongs to the TMEM16 family of predicted membrane proteins, that are also known as anoctamins. While little is known about the function of this gene, mutations in this gene have been associated with some cases of autosomal dominant craniocervical dystonia. Cells from individuals with a mutation in this gene exhibited abnormalities in endoplasmic reticulum-dependent calcium signaling. Studies in rat show that the rat ortholog of this protein interacts with, and modulates the activity of a sodium-activated potassium channel. Deletion of this gene caused increased pain sensitivity in the rat model system. Alternative splicing results in multiple transcript variants encoding different isoforms.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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