This is an aptamer development services to screening aptamers binds to the AP4E1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | AP4E1 |
| Alternative Names | Adaptor Related Protein Complex 4 Subunit Epsilon 1; Adaptor Related Protein Complex 4 Epsilon 1 Subunit; AP-4 Adaptor Complex Subunit Epsilon; AP-4 Complex Subunit Epsilon-1; Epsilon-Adaptin; SPG51; Adaptor-Related Protein Complex 4 Subunit Epsilon-1; Adaptor-Related Protein Complex AP-4 Epsilon; Epsilon Subunit Of AP-4; AP-4-EPSILON; CPSQ4; STUT1; AP4E1 |
| Gene ID | 23431 |
| UniProt ID | Q9UPM8 |
| Target Overview | This gene encodes a member of the adaptor complexes large subunit protein family. These proteins are components of the heterotetrameric adaptor protein complexes, which play important roles in the secretory and endocytic pathways by mediating vesicle formation and sorting of integral membrane proteins. The encoded protein is a large subunit of adaptor protein complex-4, which is associated with both clathrin- and nonclathrin-coated vesicles. Disruption of this gene may be associated with cerebral palsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |