This is an aptamer development services to screening aptamers binds to the APBB3 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | APBB3 |
| Alternative Names | Amyloid Beta Precursor Protein Binding Family B Member 3; FE65L2; Amyloid Beta (A4) Precursor Protein-Binding, Family B, Member 3; Amyloid-Beta A4 Precursor Protein-Binding Family B Member 3; Protein Fe65-Like 2; Amyloid Precursor Interacting Protein; FE65-Like Protein 2; Fe65L2; APBB3; SRA |
| Gene ID | 10307 |
| UniProt ID | O95704 |
| Target Overview | The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |