This is an aptamer development services to screening aptamers binds to the APELA with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | APELA |
| Alternative Names | Apelin Receptor Early Endogenous Ligand; ELA; Protein Elabela; Protein Toddler; Ende; Tdl; ELABELA; Toddle; APELA; TDL |
| Gene ID | 100506013 |
| UniProt ID | P0DMC3 |
| Target Overview | This gene encodes a peptide hormone that binds to the Apelin receptor. The encoded protein is required for heart development in zebrafish and has been shown to maintain self-renewal of human embryonic stem cells through activation of the PI3K/AKT pathway. Experiments in human and mouse cell lines point to additional roles for the encoded protein in angiogenesis and regulation of vascular tone. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |