Anti-API5 Aptamer SELEX Service(Cat#: CTApt-2112)

This is an aptamer development services to screening aptamers binds to the API5 with an affinity of 1nM~1μM.

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Certificate of Analysis Lookup

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Summary

Specifications
Target Category Protein
Target API5
Alternative Names Apoptosis Inhibitor 5; AAC-11; Fibroblast Growth Factor 2-Interacting Factor 2; Cell Migration-Inducing Gene 8 Protein; Migration-Inducing Protein MIG8; Antiapoptosis Clone 11 Protein; AAC11; FIF; Fibroblast Growth Factor 2-Interacting Factor; Protein XAG; API5-Like ; API5L1; API-5; API5
Gene ID 8539
UniProt ID Q9BZZ5
Target Overview This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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