Anti-APLNR Aptamer SELEX Service(Cat#: CTApt-2114)

This is an aptamer development services to screening aptamers binds to the APLNR with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target APLNR
Alternative Names Apelin Receptor; APJ; G-Protein Coupled Receptor HG11; Angiotensin II Receptor-Like 1; Angiotensin Receptor-Like 1; APJ (Apelin) Receptor; AGTRL1; APJR; G Protein-Coupled Receptor APJ; G-Protein Coupled Receptor APJ; HG11 Orphan Receptor; APJ Recepto; FLJ90771; APLNR; HG11
Gene ID 187
UniProt ID P35414
Target Overview This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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