This is an aptamer development services to screening aptamers binds to the APLP1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | APLP1 |
| Alternative Names | Amyloid Beta Precursor Like Protein 1; Amyloid-Like Protein 1; APLP; Amyloid Beta (A4) Precursor-Like Protein 1; Amyloid Precursor-Like Protein 1; APLP-1; APLP1 |
| Gene ID | 333 |
| UniProt ID | P51693 |
| Target Overview | This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |