This is an aptamer development services to screening aptamers binds to the APOA5 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | APOA5 |
| Alternative Names | Apolipoprotein A5; Apolipoprotein A-V; RAP3; Regeneration-Associated Protein 3; Apo-AV; Apolipoprotein A-V Precursor Variant 3; APOA-; ApoA-V; APOAV; APOA5 |
| Gene ID | 116519 |
| UniProt ID | Q6Q788 |
| Target Overview | The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |